The 23-year-old footballer collapsed with several minutes remaining in the first half of the between Tottenham Hotspur and Bolton last night.
Players rushed to his aid and looked on in horror as medics worked to resuscitate the former England Under-21 star in front of a packed crowd of 36,000 fans.
He received prolonged resuscitation at the ground and while on route to The London Chest Hospital where his heart eventually started working.
As per normal procedure, he remains anaesthetised in intensive care where he will be for the next 24-hours.
Club manager Owen Coyle said outside the London Chest Hospital: 'Fabrice is critically ill. The next 24 hours are going to be absolutely crucial.
'We've obviously been inundated with people wishing him well and we hope that if everybody can pray strongly tonight that Fabrice is able to recover.
'It's very serious. There's not getting away from that. He's critically ill and God willing he makes it through.'
Muamba's fiancee Shauna and his family attended the hospital but it is not known if his son Joshua has been to see him.
Mr Coyle added: 'Fabrice's family have asked me to pass on their thanks for the many, many kind messages of support from not only Bolton fans but also fans from clubs across the country and abroad.
'All our thoughts and prayers are for Fabrice and his family at this time. The family would also like to thank the media for respecting their privacy at this time.'
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